The Baeyer-Villiger Monooxygenases (BVMOs) are enzymes belonging to the "Class B" of flavin monooxygenases and are capable of performing exquisite selective oxidations.These enzymes have been studied from a biotechnological perspective, but their physiological substrates and functional roles are widely unknown.Here, we investigated the origin, taxo
FEDERALISM IN RUSSIA AND EVOLUTION OF THE REGIONAL STATEHOOD: THE CASE OF REPUBLIC OF DAGESTAN
Approaches to the optimization of the federal government system should ensure increasing efficiency of the authorities at both federal and regional levels.The peculiar feature of federalism in Russia is that Russia includes ethnic republics where population is strongly driven by local traditions.It is impossible to ignore such ethnic traditions at
Cardiovascular effects in patrol officers are associated with fine particulate matter from brake wear and engine emissions
Abstract Background Exposure to fine particulate matter air pollutants (PM2.5) affects heart rate variability parameters, and levels of serum proteins associated with inflammation, hemostasis and thrombosis.This study investigated sources potentially responsible for cardiovascular and Wrapping Paper hematological effects in highway patrol troopers.
The Teaching Model through Problem-Based Learning in a Course on Bibliographic Research
The experience of applying problem-based learning (PBL) technique in the Bibliographic Research course from a Bachelor of English study plan of a public university during the first half of 2014 is shared.The investigation aimed to answer the following question: Does the problem-based learning General technique in the Bibliographic Research course a
TMBcat: A multi-endpoint p-value criterion on different discrepancy metrics for superiorly inferring tumor mutation burden thresholds
Tumor mutation burden (TMB) is a widely recognized stratification biomarker for predicting the efficacy of immunotherapy; however, the number and universal definition of the categorizing thresholds remain debatable due to the multifaceted nature of efficacy and the imprecision of TMB measurements.We proposed a minimal joint p-value criterion from t